Know-How

Incorporation of fluorine atom(s) into a molecule could considerably modify its physico-chemical and biological properties, and so the use of fluorine in potential drugs or for crop-protection is increasing.

Continuous efforts are being made to  develop new and more efficient synthetic tools for the synthesis of novel fluorinated biologically active compounds.

Innov’Orga proposes its expertise and knowledge in fluorine organic chemistry:

• Innov’Orga offers a distinctive range of new fluorinated organic synthetic tools. In addition to our catalogue, we offer contract research and custom synthesis services.
  

• Innov’Orga is also interested in molecules being able to enter in the synthesis of new potential candidate drugs for the treatment of neurodegenerative deseases. In this context,  Innov'orga develops unique libraries of fluorinated organic compounds with high therapeutic potential.

• Fluorination methods
  

- Nucleophilic fluorination methods (Halogen exchange reaction with 3HF-NEt₃, DAST, ...)

- Electrophilic fluorination methods (NFSI, Selectfluor^®, ...)

• Trifluoromethylation methods
  

• Heterocyclic chemistry
  

• Perfluoroketene dithioacetals
  

• Synthesis of various Perfluorinated building blocks
  

• ...